A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.14.11.44
| Accepted Name |
|---|
| (R)-dichlorprop dioxygenase (2-oxoglutarate).
|
| Alternative Name(s) |
|---|
| (R)-mecoprop dioxygenase. |
| (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase. |
| 2-oxoglutarate-dependent (R)-dichlorprop dioxygenase. |
| 2-oxoglutarate-dependent (R)-mecoprop dioxygenase. |
| Alpha-ketoglutarate-dependent (R)-dichlorprop dioxygenase. |
| Reaction catalysed |
|---|
- (R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O(2) <=> 4-chloro-2-methylphenol + pyruvate + succinate + CO(2)
- (R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O(2) <=> 2,4-dichlorophenol + pyruvate + succinate + CO(2)
|
| Cofactor(s) |
|---|
| Fe(2+).
|
| Comment(s) |
|---|
| The enzymes from the Gram-negative bacteria Delftia acidovorans MC1
and Sphingomonas herbicidovorans MH are involved in the degradation
of the (R)-enantiomer of the phenoxyalkanoic acid herbicides mecoprop
and dichlorprop.
|
| Cross-references |
|---|
| BRENDA | 1.14.11.44 |
| EC2PDB | 1.14.11.44 |
| ExplorEnz | 1.14.11.44 |
| PRIAM enzyme-specific profiles | 1.14.11.44 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.11.44 |
| IUBMB Enzyme Nomenclature | 1.14.11.44 |
| IntEnz | 1.14.11.44 |
| MEDLINE | Find literature relating to 1.14.11.44 |
| MetaCyc | 1.14.11.44 |
| UniProtKB/Swiss-Prot |
|
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