Expasy logo

ENZYME

ENZYME entry: EC 1.14.11.45

Accepted Name
L-isoleucine 4-hydroxylase
Reaction catalysed
2-oxoglutarate + L-isoleucine + O2 = (4S)-4-hydroxy-L-isoleucine + CO2 + succinate
Comment(s)
The enzyme, characterized from the bacterium Bacillus thuringiensis, can also catalyze the hydroxylation of L-leucine, L-norvaline, L-norleucine, and L-allo-isoleucine, as well as the sulfoxidation of L-methionine, L-ethionine, S-methyl-L-cysteine, S-ethyl-L-cysteine, and S-allyl-L-cysteine.
Cross-references
BRENDA1.14.11.45
EC2PDB1.14.11.45
ExplorEnz1.14.11.45
PRIAM enzyme-specific profiles1.14.11.45
KEGG Ligand Database for Enzyme Nomenclature1.14.11.45
IUBMB Enzyme Nomenclature1.14.11.45
IntEnz1.14.11.45
MEDLINEFind literature relating to 1.14.11.45
MetaCyc1.14.11.45
Rhea expert-curated reactions1.14.11.45
UniProtKB/Swiss-Prot
E2GIN1, IDO_BACTU

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-