ID   1.14.11.49
DE   uridine-5'-phosphate dioxygenase.
CA   2-oxoglutarate + O2 + UMP = CO2 + phosphate + succinate + uridine-
CA   5'-aldehyde.
CC   -!- The enzyme catalyzes a net dephosphorylation and oxidation of UMP to
CC       generate 5'-dehydrouridine, the first intermediate in the
CC       biosynthesis of the unusual aminoribosyl moiety found in several
CC       C(7)-furanosyl nucleosides such as A-90289s, caprazamycins,
CC       liposidomycins, muraymycins and FR-900453.
DR   A0A0E3USC3, UMPDO_AMYSP;  D4QF25, UMPDO_STRSQ;
//