Due to work on this service, it may not be fully operational on Wednesday March 20 between 1.30 pm and 2.30 pm CEST
. Apologies for the incovenience.
A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 188.8.131.52
View entry in original ENZYME format
View entry in raw text format (no links)
|mRNA N(6)-methyladenine demethylase.
|N(6)-methyladenosine in mRNA + 2-oxoglutarate + O(2) <=> adenosine in mRNA + formaldehyde + succinate + CO(2)|
- Catalyzes oxidative demethylation of mRNA N(6)-methyladenine.
- The FTO enzyme from human can also demethylate N(3)-methylthymine
from single stranded DNA and N(3)-methyluridine from single stranded
RNA with low activity.
|PRIAM enzyme-specific profiles||184.108.40.206|
|KEGG Ligand Database for Enzyme Nomenclature||220.127.116.11|
|IUBMB Enzyme Nomenclature||18.104.22.168|
|MEDLINE||Find literature relating to 22.214.171.124|
entries corresponding to 1.14.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-