A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.14.11.6
| Accepted Name |
|---|
| Thymine dioxygenase.
|
| Alternative Name(s) |
|---|
| Thymine 7-hydroxylase. |
| Thymine,2-oxoglutarate dioxygenase. |
| Reaction catalysed |
|---|
| Thymine + 2-oxoglutarate + O(2) <=> 5-hydroxymethyluracil + succinate + CO(2) |
| Cofactor(s) |
|---|
| Fe(2+); L-ascorbate.
|
| Comment(s) |
|---|
- Also acts on 5-hydroxymethyluracil to oxidize its -CH(2)-OH group
first to -CHO and then to -COOH.
- Formerly EC 1.14.11.5.
|
| Cross-references |
|---|
| BRENDA | 1.14.11.6 |
| EC2PDB | 1.14.11.6 |
| ExplorEnz | 1.14.11.6 |
| PRIAM enzyme-specific profiles | 1.14.11.6 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.11.6 |
| IUBMB Enzyme Nomenclature | 1.14.11.6 |
| IntEnz | 1.14.11.6 |
| MEDLINE | Find literature relating to 1.14.11.6 |
| MetaCyc | 1.14.11.6 |
| UniProtKB/Swiss-Prot |
| Q4DBW3, JBP1A_TRYCC; | Q4DLX9, JBP1B_TRYCC; | Q9U6M2, JBP1_CRIFA; |
| A4H5X5, JBP1_LEIBR; | A4HU70, JBP1_LEIIN; | Q4QHM7, JBP1_LEIMA; |
| Q9U6M1, JBP1_LEITA; | P86938, JBP1_TRYB2; | P86937, JBP1_TRYBB; |
| A4H7G5, JBP2_LEIBR; | A4HVU6, JBP2_LEIIN; | Q4QFY1, JBP2_LEIMA; |
| B6EU02, JBP2_LEITA; | Q57X81, JBP2_TRYB2; | Q4DCH3, JBP2_TRYCC; |
|
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