ID 1.14.11.61 DE feruloyl-CoA 6-hydroxylase. CA (E)-feruloyl-CoA + 2-oxoglutarate + O2 = (E)-6-hydroxyferuloyl-CoA + CA CO2 + succinate. CC -!- Requires iron(II) and ascorbate. CC -!- The product spontaneously undergoes trans-cis isomerization and CC lactonization to form scopoletin, liberating CoA in the process. CC -!- The enzymes from the plants Ruta graveolens and Ipomoea batatas also CC act on trans-4-coumaroyl-CoA. cf. EC 1.14.11.62. DR A0A023GS28, DIOX1_RUTGR; A0A023GS29, DIOX2_RUTGR; W5QJZ5, DIOX4_RUTGR; DR G9M9M0, F6H11_IPOBA; G9M9M1, F6H12_IPOBA; G9M9M2, F6H13_IPOBA; DR Q9LHN8, F6H1_ARATH ; G9M9M4, F6H21_IPOBA; G9M9M3, F6H22_IPOBA; DR G9M9M5, F6H28_IPOBA; Q9C899, F6H2_ARATH ; //