Expasy logo

ENZYME

ENZYME entry: EC 1.14.11.63

PURL: https://purl.expasy.org/enzyme/EC/1.14.11.63
Accepted Name
peptidyl-lysine (3S)-dioxygenase
Alternative Name(s)
JmjC domain-containing protein 7
Jumonji domain-containing protein 7
Reaction catalysed
L-lysyl-[protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-lysyl-[protein] + succinate + CO2
Comment(s)
  • Requires iron(II).
  • The enzyme acts on specific lysine residues in its substrates, and is stereo-specific.
  • The enzyme encoded by the human JMJD7 gene acts specifically on two related members of the translation factor family of GTPases, DRG1 and DRG2.
Cross-references
BRENDA1.14.11.63
EC2PDB1.14.11.63
ExplorEnz1.14.11.63
KEGG Ligand Database for Enzyme Nomenclature1.14.11.63
IUBMB Enzyme Nomenclature1.14.11.63
MEDLINEFind literature relating to 1.14.11.63
MetaCyc1.14.11.63
Rhea expert-curated reactions1.14.11.63
UniProtKB/Swiss-Prot
Q9VU77, JMJD7_DROMEP0C870, JMJD7_HUMANP0C872, JMJD7_MOUSE

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.11.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-