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ENZYME

ENZYME entry: EC 1.14.11.64

PURL: https://purl.expasy.org/enzyme/EC/1.14.11.64
Accepted Name
glutarate dioxygenase
Reaction catalysed
glutarate + 2-oxoglutarate + O2 = (S)-2-hydroxyglutarate + succinate + CO2
Comment(s)
  • Requires iron(II).
  • The enzyme, characterized from the bacteria Escherichia coli and Pseudomonas putida, participates in L-lysine degradation in many bacteria.
  • It provides an alternative route for L-glutarate degradation that does not proceed via CoA-activated intermediates.
Cross-references
BRENDA1.14.11.64
EC2PDB1.14.11.64
ExplorEnz1.14.11.64
KEGG Ligand Database for Enzyme Nomenclature1.14.11.64
IUBMB Enzyme Nomenclature1.14.11.64
MEDLINEFind literature relating to 1.14.11.64
MetaCyc1.14.11.64
Rhea expert-curated reactions1.14.11.64
UniProtKB/Swiss-Prot
A8ANL5, GLAH_CITK8A7ZQ90, GLAH_ECO24B7UH78, GLAH_ECO27
B7MJS0, GLAH_ECO45B7LDM7, GLAH_ECO55Q8X954, GLAH_ECO57
B5Z271, GLAH_ECO5EB7NSE0, GLAH_ECO7IB7MYW1, GLAH_ECO81
B7M9A2, GLAH_ECO8AC4ZYR1, GLAH_ECOBWB1XBW5, GLAH_ECODH
A8A3E0, GLAH_ECOHSA1AEK4, GLAH_ECOK1Q0TEL8, GLAH_ECOL5
Q8FES6, GLAH_ECOL6B1IVJ9, GLAH_ECOLCP76621, GLAH_ECOLI
B7N6P3, GLAH_ECOLUB1LPD2, GLAH_ECOSMQ1R844, GLAH_ECOUT
B7LT11, GLAH_ESCF3B5Y1D2, GLAH_KLEV3A5W454, GLAH_PSEP1
B0KUT6, GLAH_PSEPGQ88IU0, GLAH_PSEPKB4T361, GLAH_SALNS
Q5PEY3, GLAH_SALPAA9N078, GLAH_SALPBB5BEK3, GLAH_SALPK
Q8Z4G0, GLAH_SALTIE1WA38, GLAH_SALTSP0CL02, GLAH_SALTY
B2U084, GLAH_SHIB3Q83K04, GLAH_SHIFL

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