ID   1.14.11.67
DE   [histone H3]-trimethyl-L-lysine(4) demethylase.
CA   3 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] +
CA   3 O2 = 3 CO2 + 3 formaldehyde + L-lysyl(4)-[histone H3] + 3 succinate.
CC   -!- Requires iron(II).
CC   -!- This entry describes a group of enzymes that demethylate N-methylated
CC       L-lysine residues at position 4 of histone H3 (H3K4).
CC   -!- The enzymes are dioxygenases and act by hydroxylating the methyl
CC       group, forming an unstable hemiaminal that leaves as formaldehyde.
CC   -!- They can act on tri-, di-, and mono-methylated forms.
DR   P47156, JHD2_YEAST ;  Q53WJ1, JM703_ORYSJ;  Q8GUI6, JMJ14_ARATH;
DR   F4I240, JMJ17_ARATH;  Q6IQX0, KD5BB_DANRE;  P29375, KDM5A_HUMAN;
DR   Q3UXZ9, KDM5A_MOUSE;  Q5F3R2, KDM5B_CHICK;  Q9UGL1, KDM5B_HUMAN;
DR   Q80Y84, KDM5B_MOUSE;  Q38JA7, KDM5C_CANLF;  P41228, KDM5C_CRIGR;
DR   P41229, KDM5C_HUMAN;  P41230, KDM5C_MOUSE;  A1YVX4, KDM5C_PIG  ;
DR   Q30DN6, KDM5D_CANLF;  Q9BY66, KDM5D_HUMAN;  Q62240, KDM5D_MOUSE;
DR   Q5XUN4, KDM5D_PANTR;  Q61T02, KDM5_CAEBR ;  Q23541, KDM5_CAEEL ;
DR   Q9VMJ7, KDM5_DROME ;
//