ID   1.14.11.77
DE   alkyl sulfatase.
AN   2-oxoglutarate-dependent sulfate ester dioxygenase.
AN   alpha-ketoglutarate-dependent sulfate ester dioxygenase.
AN   type II alkyl sulfatase.
CA   2-oxoglutarate + a primary linear alkyl sulfate ester + O2 = an aldehyde
CA   + CO2 + H(+) + succinate + sulfate.
CC   -!- Sulfatase enzymes are classified as type I, in which the key
CC       catalytic residue is 3-oxo-L-alanine, type II, which are non-heme
CC       iron-dependent dioxygenases, or type III, whose catalytic domain
CC       adopts a metallo-beta-lactamase fold and binds two zinc ions as
CC       cofactors.
CC   -!- The type II sulfatases oxidize the C-H bond of the carbon next to the
CC       sulfate ester, using 2-oxoglutarate and oxygen as substrates.
CC   -!- The resulting hemiacetal sulfate ester collapses, liberating
CC       inorganic sulfate and an alkyl aldehyde along with carbon dioxide and
CC       succinate.
CC   -!- The enzymes often desulfate a broad spectrum of linear and branched-
CC       chain sulfate esters.
CC   -!- The enzyme from Pseudomonas putida acts on a range of medium-chain
CC       alkyl sulfate esters, with chain lengths ranging from C4 to C12. cf.
CC       sulfatase EC 3.1.6.1, EC 3.1.6.21, and EC 3.1.6.22.
DR   P65076, ATSK_MYCBO ;  P9WKZ0, ATSK_MYCTO ;  P9WKZ1, ATSK_MYCTU ;
DR   Q9WWU5, ATSK_PSEPU ;
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