ID   1.14.11.79
DE   protein-L-histidine (3S)-3-hydroxylase.
AN   protein histidyl hydroxylase.
CA   2-oxoglutarate + L-histidyl-[protein] + O2 = (3S)-3-hydroxy-L-histidyl-
CA   [protein] + CO2 + succinate.
CC   -!- The human enzymes encoded by the RIOX1 and RIOX2 genes catalyze the
CC       hydroxylation of L-histidine residues in the 60S ribosomal proteins
CC       Rpl8 and L27a, respectively.
CC   -!- Both proteins contain JmjC and winged helix domains, and both also
CC       catalyze histone L-lysine demethylation activities.
DR   A5PK74, RIOX1_BOVIN;  Q5ZMM1, RIOX1_CHICK;  A3KP59, RIOX1_DANRE;
DR   Q9H6W3, RIOX1_HUMAN;  Q9JJF3, RIOX1_MOUSE;  D3ZU57, RIOX1_RAT  ;
DR   Q5EA24, RIOX2_BOVIN;  Q8IUF8, RIOX2_HUMAN;  Q8CD15, RIOX2_MOUSE;
DR   Q5R673, RIOX2_PONAB;  Q8CFC1, RIOX2_RAT  ;
//