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ENZYME

ENZYME entry: EC 1.14.11.n4

PURL: https://purl.expasy.org/enzyme/EC/1.14.11.n4
Accepted Name
ankyrin-repeat-histidine dioxagenase
Reaction catalysed
  • L-histidyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-histidyl-[ankyrin-repeat domain protein] + succinate + CO2
  • L-asparaginyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-asparaginyl-[ankyrin-repeat domain protein] + succinate + CO2
  • L-aspartyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + succinate + CO2
Cross-references
UniProtKB/Swiss-Prot
P59723, HIF1N_DANREQ9NWT6, HIF1N_HUMANQ8BLR9, HIF1N_MOUSE

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