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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.14.12.11

Accepted Name
Toluene dioxygenase.
Alternative Name(s)
Toluene 1,2-dioxygenase.
Reaction catalysed
Toluene + NADH + O(2) <=> (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+)
Comment(s)
  • A system, containing a reductase which is an iron-sulfur flavoprotein (FAD), an iron-sulfur oxygenase, and a ferredoxin.
  • Some other aromatic compounds, including ethylbenzene, 4-xylene and some halogenated toluenes, are converted into the corresponding cis- dihydrodiols.
Cross-references
BRENDA1.14.12.11
EC2PDB1.14.12.11
ExplorEnz1.14.12.11
PRIAM enzyme-specific profiles1.14.12.11
KEGG Ligand Database for Enzyme Nomenclature1.14.12.11
IUBMB Enzyme Nomenclature1.14.12.11
IntEnz1.14.12.11
MEDLINEFind literature relating to 1.14.12.11
MetaCyc1.14.12.11
UniProtKB/Swiss-Prot
A5W4F2, BNZA_PSEP1;  P0C618, BNZA_PSEPU;  A5W4F1, BNZB_PSEP1;  
P0C619, BNZB_PSEPU;  

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