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ENZYME entry: EC 1.14.12.16

Accepted Name
2-hydroxyquinoline 5,6-dioxygenase.
Alternative Name(s)
2-oxo-1,2-dihydroquinoline 5,6-dioxygenase.
Quinolin-2(1H)-one 5,6-dioxygenase.
Quinolin-2-ol 5,6-dioxygenase.
Reaction catalysed
Quinolin-2-ol + NADH + O(2) <=> 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD(+)
Comment(s)
  • 3-methylquinolin-2-ol, quinolin-8-ol and quinolin-2,8-diol are also substrates.
  • Quinolin-2-ols exist largely as their quinolin-2(1H)-one tautomers.
Cross-references
BRENDA1.14.12.16
EC2PDB1.14.12.16
ExplorEnz1.14.12.16
PRIAM enzyme-specific profiles1.14.12.16
KEGG Ligand Database for Enzyme Nomenclature1.14.12.16
IUBMB Enzyme Nomenclature1.14.12.16
IntEnz1.14.12.16
MEDLINEFind literature relating to 1.14.12.16
MetaCyc1.14.12.16
Rhea expert-curated reactions1.14.12.16

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.12.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-