ID 1.14.12.18 DE biphenyl 2,3-dioxygenase. AN biphenyl dioxygenase. CA biphenyl + H(+) + NADH + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2- CA diol + NAD(+). CC -!- The enzyme from Burkholderia fungorum strain LB400 (previously CC Pseudomonas sp.) is part of a multicomponent system composed of an CC NADH:ferredoxin oxidoreductase (FAD cofactor), a [2Fe-2S] Rieske-type CC ferredoxin, and a terminal oxygenase that contains a [2Fe-2S] Rieske- CC type iron-sulfur cluster and a catalytic mononuclear nonheme iron CC center. CC -!- Chlorine-substituted biphenyls can also act as substrates. CC -!- Similar to the three-component enzyme systems EC 1.14.12.3 and CC EC 1.14.12.11. DR Q52438, BPHA1_PSES1; Q53122, BPHA1_RHOJR; Q52439, BPHA2_PSES1; DR Q53123, BPHA2_RHOJR; Q46372, BPHA_COMTE ; P37333, BPHA_PARXL ; DR Q52028, BPHA_PSEFK ; Q46373, BPHE_COMTE ; P37334, BPHE_PARXL ; //