ENZYME entry: EC 1.14.12.19
| Accepted Name |
|---|
| 3-phenylpropanoate dioxygenase.
|
| Alternative Name(s) |
|---|
| 3-phenylpropionate dioxygenase. |
| HcaA1A2CD. |
| Hca dioxygenase. |
| Reaction catalysed |
|---|
- 3-phenylpropanoate + H(+) + NADH + O2 <=> 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+)
- (E)-cinnamate + H(+) + NADH + O2 <=> (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+)
|
| Comment(s) |
|---|
- This enzyme catalyzes a step in the pathway of phenylpropanoid
compounds degradation.
- It catalyzes the insertion of both atoms of molecular oxygen into
positions 2 and 3 of the phenyl ring of 3-phenylpropanoate or (2E)-3-
phenylprop-2-enoate.
|
| Cross-references |
|---|
| BRENDA | 1.14.12.19 |
| EC2PDB | 1.14.12.19 |
| ExplorEnz | 1.14.12.19 |
| PRIAM enzyme-specific profiles | 1.14.12.19 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.12.19 |
| IUBMB Enzyme Nomenclature | 1.14.12.19 |
| IntEnz | 1.14.12.19 |
| MEDLINE | Find literature relating to 1.14.12.19 |
| MetaCyc | 1.14.12.19 |
| Rhea expert-curated reactions | 1.14.12.19 |
| UniProtKB/Swiss-Prot |
| P0ABR6, HCAE_ECO57; | A8A344, HCAE_ECOHS; | P0ABR5, HCAE_ECOLI; |
| Q7N4W0, HCAE_PHOLL; | Q31XV2, HCAE_SHIBS; | Q0T1Y1, HCAE_SHIF8; |
| Q83K39, HCAE_SHIFL; | Q3YZ15, HCAE_SHISS; | A7ZPY2, HCAF_ECO24; |
| B7LDD1, HCAF_ECO55; | Q8XA73, HCAF_ECO57; | B5Z112, HCAF_ECO5E; |
| B7NRI8, HCAF_ECO7I; | B7M7P2, HCAF_ECO8A; | C4ZXB4, HCAF_ECOBW; |
| B1XB14, HCAF_ECODH; | A8A345, HCAF_ECOHS; | B1IVT8, HCAF_ECOLC; |
| Q47140, HCAF_ECOLI; | B7N6C6, HCAF_ECOLU; | B6I5B2, HCAF_ECOSE; |
| B1LNJ5, HCAF_ECOSM; | Q7N4V9, HCAF_PHOLL; | Q31XV1, HCAF_SHIBS; |
| Q0T1Y0, HCAF_SHIF8; | Q83K38, HCAF_SHIFL; | Q3YZ14, HCAF_SHISS; |
|
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