Home  |  Contact
Due to scheduled maintenance work, this service will not be available from Tuesday August 23rd 06:00 pm until Wednesday August 24th 08:00 am CEST. Apologies for the inconvenience.

ENZYME entry: EC

Accepted Name
nitroarene dioxygenase.
Reaction catalysed
NADH + nitrobenzene + O2 <=> catechol + NAD(+) + nitrite
  • This enzyme is a member of the naphthalene family of bacterial Rieske non-heme iron dioxygenases.
  • It comprises a multicomponent system, containing a Rieske [2Fe-2S] ferredoxin, an NADH-dependent flavoprotein reductase (EC, and an alpha3beta3 oxygenase.
  • The enzyme forms of a cis-dihydroxylated product that spontaneously rearranges to form a catechol with accompanying release of nitrite.
  • It can typically act on many different nitroaromatic compounds, including chlorinated species.
  • Enzymes found in different strains may have different substrate preferences.
PRIAM enzyme-specific profiles1.14.12.23
KEGG Ligand Database for Enzyme Nomenclature1.14.12.23
IUBMB Enzyme Nomenclature1.14.12.23
MEDLINEFind literature relating to
Rhea expert-curated reactions1.14.12.23

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.12.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-