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ENZYME

ENZYME entry: EC 1.14.13.166

Accepted Name
4-nitrocatechol 4-monooxygenase
Reaction catalysed
  • 4-nitrocatechol + NADPH + O2 <=> 2-hydroxy-1,4-benzoquinone + H2O + NADP(+) + nitrite
  • 4-nitrocatechol + NADH + O2 <=> 2-hydroxy-1,4-benzoquinone + H2O + NAD(+) + nitrite
Comment(s)
  • The enzyme catalyzes the oxidation of 4-nitrocatechol with the concomitant removal of the nitro group as nitrite.
  • Forms a two-component system with a flavoprotein reductase.
  • The enzymes from the bacteria Lysinibacillus sphaericus JS905 and Rhodococcus sp. strain PN1 were shown to also catalyze EC 1.14.13.29, while the enzyme from Pseudomonas sp. WBC-3 was shown to also catalyze EC 1.14.13.167.
Cross-references
BRENDA1.14.13.166
EC2PDB1.14.13.166
ExplorEnz1.14.13.166
PRIAM enzyme-specific profiles1.14.13.166
KEGG Ligand Database for Enzyme Nomenclature1.14.13.166
IUBMB Enzyme Nomenclature1.14.13.166
IntEnz1.14.13.166
MEDLINEFind literature relating to 1.14.13.166
MetaCyc1.14.13.166
Rhea expert-curated reactions1.14.13.166
UniProtKB/Swiss-Prot
Q6F4M8, NPCA_RHOOPQ6F4M9, NPCB_RHOOP

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