ENZYME entry: EC 1.14.13.180
| Accepted Name |
|---|
| Aklavinone 12-hydroxylase.
|
| Alternative Name(s) |
|---|
| Aklavinone 11-hydroxylase. |
| Reaction catalysed |
|---|
| Aklavinone + NADPH + O(2) <=> epsilon-rhodomycinone + NADP(+) + H(2)O |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
| The enzymes from the Gram-positive bacteria Streptomyces peucetius
and Streptomyces purpurascens participate in the biosynthesis of
daunorubicin, doxorubicin and rhodomycins.
|
| Cross-references |
|---|
| BRENDA | 1.14.13.180 |
| EC2PDB | 1.14.13.180 |
| ExplorEnz | 1.14.13.180 |
| PRIAM enzyme-specific profiles | 1.14.13.180 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.180 |
| IUBMB Enzyme Nomenclature | 1.14.13.180 |
| IntEnz | 1.14.13.180 |
| MEDLINE | Find literature relating to 1.14.13.180 |
| MetaCyc | 1.14.13.180 |
| UniProtKB/Swiss-Prot |
|
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