ID 1.14.13.196 DE L-ornithine N(5)-monooxygenase (NAD(P)H). CA L-ornithine + NAD(P)H + O(2) = N(5)-hydroxy-L-ornithine + NAD(P)(+) + CA H(2)O. CF FAD. CC -!- The enzyme from the pathogenic fungus Aspergillus fumigatus catalyzes CC a step in the biosynthesis of the siderophores triacetylfusarinine CC and desferriferricrocin, while the enzyme from the bacterium CC Kutzneria sp. 744 is involved in the biosynthesis of piperazate, CC a building block of the kutzneride family of antifungal antibiotics. CC -!- Activity of the fungal enzyme is higher with NADPH, due to the fact CC that following the reduction of the flavin, NADP(+) (but not NAD(+)) CC stabilizes the C4a-hydroperoxyflavin intermediate that oxidizes the CC substrate. CC -!- Cf. EC 1.14.13.195. DR A8NF99, CPF2_COPC7 ; N4WYI1, SIDA2_COCH4; B2KWI1, SIDA_AJECA ; DR D4AU57, SIDA_ARTBC ; E9QYP0, SIDA_ASPFU ; Q2TZB2, SIDA_ASPOR ; DR M2PP75, SIDA_CERS8 ; G5EB76, SIDA_EMENI ; I1RN13, SIDA_GIBZE ; DR Q52UT0, SIDA_OMPOL ; Q9P7T0, SIDA_SCHPO ; P56584, SIDA_USTMA ; //