ID   1.14.13.196
DE   L-ornithine N(5)-monooxygenase [NAD(P)H].
CA   (1) L-ornithine + NADPH + O2 = N(5)-hydroxy-L-ornithine + NADP(+) + H2O.
CA   (2) L-ornithine + NADH + O2 = N(5)-hydroxy-L-ornithine + NAD(+) + H2O.
CC   -!- The enzyme from the pathogenic fungus Aspergillus fumigatus catalyzes
CC       a step in the biosynthesis of the siderophores triacetylfusarinine
CC       and desferriferricrocin, while the enzyme from the bacterium
CC       Kutzneria sp. 744 is involved in the biosynthesis of piperazate,
CC       a building block of the kutzneride family of antifungal antibiotics.
CC   -!- Activity of the fungal enzyme is higher with NADPH, due to the fact
CC       that following the reduction of the flavin, NADP(+) (but not NAD(+))
CC       stabilizes the C4a-hydroperoxyflavin intermediate that oxidizes the
CC       substrate. cf. EC 1.14.13.195.
DR   G1XSR6, AO414_ARTOA;  A8NF99, CPF2_COPC7 ;  N4WYI1, SIDA2_COCH4;
DR   B2KWI1, SIDA_AJECA ;  D4AU57, SIDA_ARTBC ;  E9QYP0, SIDA_ASPFU ;
DR   Q2TZB2, SIDA_ASPOR ;  J4W6X9, SIDA_BEAB2 ;  M2PP75, SIDA_CERS8 ;
DR   G5EB76, SIDA_EMENI ;  I1RN13, SIDA_GIBZE ;  P56584, SIDA_MYCMD ;
DR   Q52UT0, SIDA_OMPOL ;  Q9P7T0, SIDA_SCHPO ;
//