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ENZYME

ENZYME entry: EC 1.14.13.210

Accepted Name
4-methyl-5-nitrocatechol 5-monooxygenase
Alternative Name(s)
4-methyl-5-nitrocatechol oxygenase
MNC monooxygenase
Reaction catalysed
  • 4-methyl-5-nitrocatechol + NADPH + O2 = 2-hydroxy-5-methylquinone + H(+) + H2O + NADP(+) + nitrite
  • 4-methyl-5-nitrocatechol + NADH + O2 = 2-hydroxy-5-methylquinone + H(+) + H2O + NAD(+) + nitrite
Comment(s)
  • The enzyme, isolated from the bacterium Burkholderia sp. DNT, can use both NADH and NADPH, but prefers NADPH.
  • It has a narrow substrate range, but can also act on 4-nitrocatechol.
Cross-references
BRENDA1.14.13.210
EC2PDB1.14.13.210
ExplorEnz1.14.13.210
PRIAM enzyme-specific profiles1.14.13.210
KEGG Ligand Database for Enzyme Nomenclature1.14.13.210
IUBMB Enzyme Nomenclature1.14.13.210
IntEnz1.14.13.210
MEDLINEFind literature relating to 1.14.13.210
MetaCyc1.14.13.210
Rhea expert-curated reactions1.14.13.210
UniProtKB/Swiss-Prot
Q2PWU9, DNTB_BURSP

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