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ENZYME entry: EC 1.14.13.218

Accepted Name
5-methylphenazine-1-carboxylate 1-monooxygenase.
Reaction catalysed
5-methylphenazine-1-carboxylate + NADH + O(2) <=> pyocyanine + NAD(+) + CO(2) + H(2)O
Comment(s)
  • The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in the biosynthesis of pyocyanin, a toxin produced and secreted by the organism.
  • It can also act on phenazine-1-carboxylate, converting it into 1-hydroxyphenazine.
Cross-references
BRENDA1.14.13.218
EC2PDB1.14.13.218
ExplorEnz1.14.13.218
PRIAM enzyme-specific profiles1.14.13.218
KEGG Ligand Database for Enzyme Nomenclature1.14.13.218
IUBMB Enzyme Nomenclature1.14.13.218
IntEnz1.14.13.218
MEDLINEFind literature relating to 1.14.13.218
MetaCyc1.14.13.218
UniProtKB/Swiss-Prot
Q9HWG9, PHZS_PSEAE

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