ID   1.14.13.222
DE   aurachin C monooxygenase/isomerase.
AN   aurachin C monooxygenase.
CA   (1) aurachin C + NADH + O2 + H(+) = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-
CA   farnesyl]-3,4-dihydroquinoline 1-oxide + NAD(+) + H2O.
CA   (2) aurachin C + NADPH + O2 + H(+) = 4-hydroxy-2-methyl-3-oxo-4-[(2E,6E)-
CA   farnesyl]-3,4-dihydroquinoline 1-oxide + NADP(+) + H2O.
CC   -!- The aurachin C monooxygenase from the bacterium Stigmatella
CC       aurantiaca accepts both NADH and NADPH as cofactor, but has a
CC       preference for NADH.
CC   -!- It catalyzes the initial steps in the conversion of aurachin C to
CC       aurachin B.
CC   -!- The FAD-dependent monooxygenase catalyzes the epoxidation of the
CC       C2-C3 double bond of aurachin C, which is followed by a semipinacol
CC       rearrangement, causing migration of the farnesyl group from C3 to C4.
DR   H1ZZA4, AUAG_STIAU ;
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