ENZYME entry: EC 1.14.13.223
| Accepted Name |
|---|
| 3-hydroxy-4-methyl-anthranilyl-[aryl-carrier protein] 5-monooxygenase.
|
| Reaction catalysed |
|---|
| 3-hydroxy-4-methyl-anthranilyl-[aryl-carrier protein] + NADH + O(2) <=> 3,5-dihydroxy-4-methyl-anthranilyl-[aryl-carrier protein] + NAD(+) + H(2)O |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- The enzyme, characterized from the bacterium Streptosporangium
sibiricum, is involved in the biosynthesis of the antitumor
antibiotic sibiromycin.
- The enzyme is not active with free 3-hydroxy-4-methylanthranilate.
|
| Cross-references |
|---|
| BRENDA | 1.14.13.223 |
| EC2PDB | 1.14.13.223 |
| ExplorEnz | 1.14.13.223 |
| PRIAM enzyme-specific profiles | 1.14.13.223 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.13.223 |
| IUBMB Enzyme Nomenclature | 1.14.13.223 |
| IntEnz | 1.14.13.223 |
| MEDLINE | Find literature relating to 1.14.13.223 |
| MetaCyc | 1.14.13.223 |
| Rhea expert-curated reactions | 1.14.13.223 |
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