ID   1.14.13.225
DE   F-actin monooxygenase.
CA   H(+) + L-methionyl-[F-actin] + NADPH + O2 = H2O + L-methionyl-(R)-S-
CA   oxide-[F-actin] + NADP(+).
CC   -!- The enzyme, characterized from the fruit fly Drosophila melanogaster,
CC       is a multi-domain oxidoreductase that acts as an F-actin disassembly
CC       factor.
CC   -!- The enzyme selectively reduces two L-Met residues of F-actin, causing
CC       fragmentation of the filaments and preventing repolymerization.
CC   -!- Free methionine is not a substrate.
CC   -!- The reaction is stereospecific and generates the (R)-sulfoxide.
DR   F1RA39, MCA2B_DANRE;  F1QH17, MCA3A_DANRE;  F1QWK4, MCA3B_DANRE;
DR   F1MH07, MICA1_BOVIN;  E7F9T0, MICA1_DANRE;  Q8TDZ2, MICA1_HUMAN;
DR   Q8VDP3, MICA1_MOUSE;  D3ZBP4, MICA1_RAT  ;  F1MF74, MICA2_BOVIN;
DR   O94851, MICA2_HUMAN;  Q8BML1, MICA2_MOUSE;  D4A1F2, MICA2_RAT  ;
DR   F6QZ15, MICA2_XENTR;  G3MWR8, MICA3_BOVIN;  Q7RTP6, MICA3_HUMAN;
DR   Q8CJ19, MICA3_MOUSE;  Q86BA1, MICAL_DROME;
//