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ENZYME entry: EC 1.14.13.236

Accepted Name
Toluene 4-monooxygenase.
Alternative Name(s)
TMO.
Reaction catalysed
Toluene + NADH + O(2) <=> 4-methylphenol + NAD(+) + H(2)O
Cofactor(s)
Fe(2+).
Comment(s)
  • This bacterial enzyme belongs to a family of soluble diiron hydroxylases that includes toluene-, benzene-, xylene- and methane monooxygenases, phenol hydroxylases, and alkene epoxidases.
  • The enzyme comprises a four-component complex that includes a hydroxylase, NADH-ferredoxin oxidoreductase, a Rieske-type [2Fe-2S] ferredoxin, and an effector protein.
Cross-references
BRENDA1.14.13.236
EC2PDB1.14.13.236
ExplorEnz1.14.13.236
PRIAM enzyme-specific profiles1.14.13.236
KEGG Ligand Database for Enzyme Nomenclature1.14.13.236
IUBMB Enzyme Nomenclature1.14.13.236
IntEnz1.14.13.236
MEDLINEFind literature relating to 1.14.13.236
MetaCyc1.14.13.236
UniProtKB/Swiss-Prot
Q00456, TMOA_PSEME;  Q00457, TMOB_PSEME;  Q00460, TMOE_PSEME;  

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