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ENZYME

ENZYME entry: EC 1.14.13.241

PURL: https://purl.expasy.org/enzyme/EC/1.14.13.241
Accepted Name
5-pyridoxate monooxygenase
Alternative Name(s)
5-pyridoxate dioxygenase
5-pyridoxate oxidase
Reaction catalysed
5-pyridoxate + NADPH + O2 = 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+)
Comment(s)
  • The enzyme, characterized from the bacterium Arthrobacter sp Cr-7, participates in the degradation of pyridoxine (vitamin B6).
  • Although the enzyme was initially thought to be a dioxygenase, oxygen-tracer experiments have suggested that it is a monooxygnase, incorporating only one oxygen atom from molecular oxygen into the product.
  • The second oxygen atom originates from a water molecule, which is regenerated during the reaction and thus does not show up in the reaction equation.
  • Formerly EC 1.14.12.5.
Cross-references
BRENDA1.14.13.241
EC2PDB1.14.13.241
ExplorEnz1.14.13.241
KEGG Ligand Database for Enzyme Nomenclature1.14.13.241
IUBMB Enzyme Nomenclature1.14.13.241
MEDLINEFind literature relating to 1.14.13.241
MetaCyc1.14.13.241
Rhea expert-curated reactions1.14.13.241

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
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