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ENZYME

ENZYME entry: EC 1.14.13.25

PURL: https://purl.expasy.org/enzyme/EC/1.14.13.25
Accepted Name
methane monooxygenase (soluble)
Alternative Name(s)
methane hydroxylase
Reaction catalysed
  • methane + NADH + O2 + H(+) = methanol + NAD(+) + H2O
  • methane + NADPH + O2 + H(+) = methanol + NADP(+) + H2O
Comment(s)
  • The enzyme is soluble, in contrast to the particulate enzyme, EC 1.14.18.3.
  • Broad specificity; many alkanes can be hydroxylated, and alkenes are converted into the corresponding epoxides; CO is oxidized to CO2, ammonia is oxidized to hydroxylamine, and some aromatic compounds and cyclic alkanes can also be hydroxylated, but more slowly.
Cross-references
BRENDA1.14.13.25
EC2PDB1.14.13.25
ExplorEnz1.14.13.25
KEGG Ligand Database for Enzyme Nomenclature1.14.13.25
IUBMB Enzyme Nomenclature1.14.13.25
MEDLINEFind literature relating to 1.14.13.25
MetaCyc1.14.13.25
Rhea expert-curated reactions1.14.13.25
UniProtKB/Swiss-Prot
P22869, MEMA_METCAP27353, MEMA_METTRP18798, MEMB_METCA
P27354, MEMB_METTRP11987, MEMG_METCAP27355, MEMG_METTR
P22868, MMOC_METCAQ53563, MMOC_METTR

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