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ENZYME entry: EC 1.14.13.33

Accepted Name
4-hydroxybenzoate 3-monooxygenase [NAD(P)H].
Alternative Name(s)
4-hydroxybenzoate 3-hydroxylase.
Reaction catalysed
  • 4-hydroxybenzoate + H(+) + NADH + O2 <=> 3,4-dihydroxybenzoate + H2O + NAD(+)
  • 4-hydroxybenzoate + H(+) + NADPH + O2 <=> 3,4-dihydroxybenzoate + H2O + NADP(+)
Comment(s)
  • The enzyme from Corynebacterium cyclohexanicum is highly specific for 4-hydroxybenzoate, but uses NADH and NADPH at approximately equal rates (cf. EC 1.14.13.2).
  • It is less specific for NADPH than EC 1.14.13.2.
Cross-references
BRENDA1.14.13.33
EC2PDB1.14.13.33
ExplorEnz1.14.13.33
PRIAM enzyme-specific profiles1.14.13.33
KEGG Ligand Database for Enzyme Nomenclature1.14.13.33
IUBMB Enzyme Nomenclature1.14.13.33
IntEnz1.14.13.33
MEDLINEFind literature relating to 1.14.13.33
MetaCyc1.14.13.33
Rhea expert-curated reactions1.14.13.33
UniProtKB/Swiss-Prot
A2QGH7, PHHA_ASPNC;  C8VBV0, PHHA_EMENI;  C4TP09, PRAI_PAESP;  

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