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ENZYME entry: EC 1.14.14.127

Accepted Name
Methyl farnesoate epoxidase.
Alternative Name(s)
CYP15A1.
Reaction catalysed
Methyl (2E,6E)-farnesoate + [reduced NADPH--hemoprotein reductase] + O(2) <=> juvenile hormone III + [oxidized NADPH--hemoprotein reductase] + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein.
  • The enzyme, found in insects except for Lepidoptera (moths and butterflies) is specific for methyl farnesoate (cf. EC 1.14.14.128).
  • Formerly EC 1.14.13.202.
Cross-references
BRENDA1.14.14.127
EC2PDB1.14.14.127
ExplorEnz1.14.14.127
PRIAM enzyme-specific profiles1.14.14.127
KEGG Ligand Database for Enzyme Nomenclature1.14.14.127
IUBMB Enzyme Nomenclature1.14.14.127
IntEnz1.14.14.127
MEDLINEFind literature relating to 1.14.14.127
MetaCyc1.14.14.127
UniProtKB/Swiss-Prot
Q6R7M4, C15A1_DIPPU

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