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ENZYME entry: EC 1.14.14.138

Accepted Name
Lithocholate 6-beta-hydroxylase.
Alternative Name(s)
6-beta-hydroxylase.
Cytochrome P450 3A10.
Lithocholate 6-beta-monooxygenase.
Lithocholic acid 6-beta-hydroxylase.
Reaction catalysed
Lithocholate + [reduced NADPH--hemoprotein reductase] + O(2) <=> 6-beta-hydroxylithocholate + [oxidized NADPH--hemoprotein reductase] + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein from Mesocricetus auratus (golden hamster).
  • Expression of the gene for this enzyme is 50-fold higher in male compared to female hamsters.
  • Formerly EC 1.14.13.94.
Cross-references
PROSITEPDOC00081
BRENDA1.14.14.138
EC2PDB1.14.14.138
ExplorEnz1.14.14.138
PRIAM enzyme-specific profiles1.14.14.138
KEGG Ligand Database for Enzyme Nomenclature1.14.14.138
IUBMB Enzyme Nomenclature1.14.14.138
IntEnz1.14.14.138
MEDLINEFind literature relating to 1.14.14.138
MetaCyc1.14.14.138
Rhea expert-curated reactions1.14.14.138
UniProtKB/Swiss-Prot
Q64148, CP3AA_MESAU

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