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ENZYME

ENZYME entry: EC 1.14.14.138

Accepted Name
lithocholate 6beta-hydroxylase
Alternative Name(s)
6beta-hydroxylase
cytochrome P450 3A10
lithocholate 6beta-monooxygenase
lithocholic acid 6beta-hydroxylase
Reaction catalysed
lithocholate + O2 + reduced [NADPH--hemoprotein reductase] <=> 6beta-hydroxylithocholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein from Mesocricetus auratus (golden hamster).
  • Expression of the gene for this enzyme is 50-fold higher in male compared to female hamsters.
  • Formerly EC 1.14.13.94.
Cross-references
BRENDA1.14.14.138
EC2PDB1.14.14.138
ExplorEnz1.14.14.138
PRIAM enzyme-specific profiles1.14.14.138
KEGG Ligand Database for Enzyme Nomenclature1.14.14.138
IUBMB Enzyme Nomenclature1.14.14.138
IntEnz1.14.14.138
MEDLINEFind literature relating to 1.14.14.138
MetaCyc1.14.14.138
Rhea expert-curated reactions1.14.14.138
UniProtKB/Swiss-Prot
Q64148, CP3AA_MESAU

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