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ENZYME entry: EC 1.14.14.140

Accepted Name
Licodione synthase.
Alternative Name(s)
(2S)-flavanone 2-hydroxylase.
CYP93B1.
Reaction catalysed
Liquiritigenin + [reduced NADPH--hemoprotein reductase] + O(2) <=> licodione + [oxidized NADPH--hemoprotein reductase] + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein isolated from licorice plants (Glycyrrhiza echinata L.).
  • The immediate product is likely 2-hydroxyliquiritigenin, which spontaneously rearranges to form licodione.
  • Formerly EC 1.14.13.87.
Cross-references
PROSITEPDOC00081
BRENDA1.14.14.140
EC2PDB1.14.14.140
ExplorEnz1.14.14.140
PRIAM enzyme-specific profiles1.14.14.140
KEGG Ligand Database for Enzyme Nomenclature1.14.14.140
IUBMB Enzyme Nomenclature1.14.14.140
IntEnz1.14.14.140
MEDLINEFind literature relating to 1.14.14.140
MetaCyc1.14.14.140
Rhea expert-curated reactions1.14.14.140
UniProtKB/Swiss-Prot
P93149, C93B1_GLYEC

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