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ENZYME

ENZYME entry: EC 1.14.14.147

Accepted Name
22alpha-hydroxysteroid 23-monooxygenase
Alternative Name(s)
3-epi-6-deoxocathasterone 23-monooxygenase
CYP90C1
CYP90D1
Reaction catalysed
  • 3-epi-6-deoxocathasterone + O2 + reduced [NADPH--hemoprotein reductase] = 6-deoxotyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
  • (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + O2 + reduced [NADPH--hemoprotein reductase] = 3-dehydro-6-deoxoteasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein involved in brassinosteroid biosynthesis in plants.
  • The enzyme has a relaxed substrate specificity, and C-23 hydroxylation can occur at different stages in the pathway.
  • In Arabidopsis thaliana two isozymes, encoded by the CYP90C1 and CYP90D1 genes, have redundant activities.
  • Formerly EC 1.14.13.112.
Cross-references
BRENDA1.14.14.147
EC2PDB1.14.14.147
ExplorEnz1.14.14.147
PRIAM enzyme-specific profiles1.14.14.147
KEGG Ligand Database for Enzyme Nomenclature1.14.14.147
IUBMB Enzyme Nomenclature1.14.14.147
IntEnz1.14.14.147
MEDLINEFind literature relating to 1.14.14.147
MetaCyc1.14.14.147
Rhea expert-curated reactions1.14.14.147
UniProtKB/Swiss-Prot
Q9M066, C90C1_ARATHQ94IA6, C90D1_ARATHI1HL09, C90D2_BRADI

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