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ENZYME entry: EC 1.14.14.148

Accepted Name
Angelicin synthase.
Alternative Name(s)
CYP71AJ4.
Reaction catalysed
(+)-columbianetin + [reduced NADPH--hemoprotein reductase] + O(2) <=> angelicin + [oxidized NADPH--hemoprotein reductase] + acetone + 2 H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • This cytochrome P450 (heme-thiolate) enzyme from wild parsnip is involved in the formation of angular furanocoumarins.
  • Attacks its substrate by syn-elimination of hydrogen from C-3'.
  • Formerly EC 1.14.13.115.
Cross-references
BRENDA1.14.14.148
EC2PDB1.14.14.148
ExplorEnz1.14.14.148
PRIAM enzyme-specific profiles1.14.14.148
KEGG Ligand Database for Enzyme Nomenclature1.14.14.148
IUBMB Enzyme Nomenclature1.14.14.148
IntEnz1.14.14.148
MEDLINEFind literature relating to 1.14.14.148
MetaCyc1.14.14.148
Rhea expert-curated reactions1.14.14.148
UniProtKB/Swiss-Prot
C0SJS3, ANGS_PASSA

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