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ENZYME entry: EC 1.14.14.15

Accepted Name
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase.
Reaction catalysed
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] + FADH2 + O(2) <=> (3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] + FAD + H(2)O
Comment(s)
The enzyme from the bacterium Streptomyces globisporus is involved in the biosynthesis of the (S)-3-chloro-5-hydroxy-beta-tyrosine moiety prior to incorporation into the chromoprotein antitumor antibiotic C-1027.
Cross-references
BRENDA1.14.14.15
EC2PDB1.14.14.15
ExplorEnz1.14.14.15
PRIAM enzyme-specific profiles1.14.14.15
KEGG Ligand Database for Enzyme Nomenclature1.14.14.15
IUBMB Enzyme Nomenclature1.14.14.15
IntEnz1.14.14.15
MEDLINEFind literature relating to 1.14.14.15
MetaCyc1.14.14.15
Rhea expert-curated reactions1.14.14.15

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-