Expasy logo

ENZYME

ENZYME entry: EC 1.14.14.15

Accepted Name
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase
Reaction catalysed
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FADH2 + O2 = (3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FAD + H(+) + H2O
Comment(s)
The enzyme from the bacterium Streptomyces globisporus is involved in the biosynthesis of the (S)-3-chloro-5-hydroxy-beta-tyrosine moiety prior to incorporation into the chromoprotein antitumor antibiotic C-1027.
Cross-references
BRENDA1.14.14.15
EC2PDB1.14.14.15
ExplorEnz1.14.14.15
PRIAM enzyme-specific profiles1.14.14.15
KEGG Ligand Database for Enzyme Nomenclature1.14.14.15
IUBMB Enzyme Nomenclature1.14.14.15
IntEnz1.14.14.15
MEDLINEFind literature relating to 1.14.14.15
MetaCyc1.14.14.15
Rhea expert-curated reactions1.14.14.15
UniProtKB/Swiss-Prot
Q8GMG6, SGCC_STRGL

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-