ENZYME entry: EC 1.14.14.15
Accepted Name | ||
---|---|---|
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase | ||
Reaction catalysed | ||
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FADH2 + O2 = (3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FAD + H(+) + H2O | ||
Comment(s) | ||
The enzyme from the bacterium Streptomyces globisporus is involved in the biosynthesis of the (S)-3-chloro-5-hydroxy-beta-tyrosine moiety prior to incorporation into the chromoprotein antitumor antibiotic C-1027. | ||
Cross-references | ||
BRENDA | 1.14.14.15 | |
EC2PDB | 1.14.14.15 | |
ExplorEnz | 1.14.14.15 | |
PRIAM enzyme-specific profiles | 1.14.14.15 | |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.15 | |
IUBMB Enzyme Nomenclature | 1.14.14.15 | |
IntEnz | 1.14.14.15 | |
MEDLINE | Find literature relating to 1.14.14.15 | |
MetaCyc | 1.14.14.15 | |
Rhea expert-curated reactions | 1.14.14.15 | |
UniProtKB/Swiss-Prot |
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