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ENZYME

ENZYME entry: EC 1.14.14.15

Accepted Name
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase
Reaction catalysed
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FADH2 + O2 <=> (3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[SgcC2 peptidyl-carrier protein] + FAD + H(+) + H2O
Comment(s)
The enzyme from the bacterium Streptomyces globisporus is involved in the biosynthesis of the (S)-3-chloro-5-hydroxy-beta-tyrosine moiety prior to incorporation into the chromoprotein antitumor antibiotic C-1027.
Cross-references
BRENDA1.14.14.15
EC2PDB1.14.14.15
ExplorEnz1.14.14.15
PRIAM enzyme-specific profiles1.14.14.15
KEGG Ligand Database for Enzyme Nomenclature1.14.14.15
IUBMB Enzyme Nomenclature1.14.14.15
IntEnz1.14.14.15
MEDLINEFind literature relating to 1.14.14.15
MetaCyc1.14.14.15
Rhea expert-curated reactions1.14.14.15
UniProtKB/Swiss-Prot
Q8GMG6, SGCC_STRGL

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