ID   1.14.14.154
DE   sterol 14alpha-demethylase.
AN   CYP51.
AN   cytochrome P450 51.
AN   lanosterol 14alpha-demethylase.
AN   lanosterol 14-demethylase.
AN   obtusufoliol 14-demethylase.
CA   a 14alpha-methyl steroid + 3 O2 + 3 reduced [NADPH--hemoprotein
CA   reductase] = a Delta(14) steroid + formate + 4 H(+) + 4 H2O + 3 oxidized
CA   [NADPH--hemoprotein reductase].
CC   -!- This cytochrome P450 (heme-thiolate) enzyme acts on a range of
CC       steroids with a 14alpha-methyl group, such as obtusifoliol and
CC       lanosterol.
CC   -!- The enzyme catalyzes a hydroxylation and a reduction of the 14alpha-
CC       methyl group, followed by a second hydroxylation, resulting in the
CC       elimination of formate and formation of a 14(15) double bond.
CC   -!- Formerly EC 1.14.13.70.
DR   Q9SAA9, CP511_ARATH;  B8N2C8, CP51A_ASPFN;  Q4WNT5, CP51A_ASPFU;
DR   Q4PJW3, CP51A_BOVIN;  I1RJR2, CP51A_GIBZE;  Q16850, CP51A_HUMAN;
DR   Q4R8S6, CP51A_MACFA;  Q8K0C4, CP51A_MOUSE;  O46420, CP51A_PIG  ;
DR   Q5RE72, CP51A_PONAB;  Q64654, CP51A_RAT  ;  B8NFL5, CP51B_ASPFN;
DR   E9QY26, CP51B_ASPFU;  I1RBR4, CP51B_GIBZE;  B8NUK6, CP51C_ASPFN;
DR   P10613, CP51_CANAL ;  P50859, CP51_CANGA ;  P14263, CP51_CANTR ;
DR   Q9UVC3, CP51_CUNEL ;  Q1ZXH9, CP51_DICDI ;  Q759W0, CP51_EREGS ;
DR   Q5UQI3, CP51_MIMIV ;  Q12664, CP51_PENIT ;  Q02315, CP51_PICKU ;
DR   Q09736, CP51_SCHPO ;  P93846, CP51_SORBI ;  Q7Z1V1, CP51_TRYCC ;
DR   O14442, CP51_UNCNE ;  P49602, CP51_USTMA ;  P93596, CP51_WHEAT ;
DR   P10614, CP51_YEAST ;  Q1JPY5, CYP51_DANRE;
//