ID   1.14.14.156
DE   tryptophan N-monooxygenase.
AN   CYP79B1.
AN   CYP79B2.
AN   CYP79B3.
AN   tryptophan N-hydroxylase.
CA   L-tryptophan + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-
CA   (indol-3-yl)acetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized
CA   [NADPH--hemoprotein reductase].
CC   -!- A cytochrome P450 (heme-thiolate) protein from the plant Arabidopsis
CC       thaliana.
CC   -!- This enzyme catalyzes two successive N-hydroxylations of
CC       L-tryptophan, the first steps in the biosynthesis of both auxin and
CC       the indole alkaloid phytoalexin camalexin.
CC   -!- The product of the two hydroxylations, N,N-dihydroxy-L-tryptophan,
CC       is extremely labile and dehydrates spontaneously.
CC   -!- The dehydrated product is then subject to a decarboxylation that
CC       produces an oxime.
CC   -!- It is still not known whether the decarboxylation is spontaneous or
CC       catalyzed by the enzyme.
CC   -!- Formerly EC 1.14.13.125 and EC 1.14.13.n2.
DR   A0A068Q605, C7968_PRUMU;  O81346, C79B2_ARATH;  Q501D8, C79B3_ARATH;
//