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ENZYME entry: EC 1.14.14.160

Accepted Name
Zealexin A1 synthase.
Alternative Name(s)
CYP71Z18.
Reaction catalysed
(S)-beta-macrocarpene + 3 O(2) + 3 [reduced NADPH--hemoprotein reductase] <=> zealexin A1 + 4 H(2)O + 3 [oxidized NADPH--hemoprotein reductase]
Comment(s)
  • A cytochrome P450 (heme thiolate) enzyme characterized from maize.
  • The enzyme sequentially oxidizes(S)-beta-macrocarpene via alcohol and aldehyde intermediates to form zealexin A1, a maize phytoalexin that provides biochemical protection against fungal infection.
Cross-references
BRENDA1.14.14.160
EC2PDB1.14.14.160
ExplorEnz1.14.14.160
PRIAM enzyme-specific profiles1.14.14.160
KEGG Ligand Database for Enzyme Nomenclature1.14.14.160
IUBMB Enzyme Nomenclature1.14.14.160
IntEnz1.14.14.160
MEDLINEFind literature relating to 1.14.14.160
MetaCyc1.14.14.160
UniProtKB/Swiss-Prot
B4FVP3, C71Z8_MAIZE

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