ENZYME entry: EC 1.14.14.161
Accepted Name |
Nepetalactol monooxygenase.
|
Alternative Name(s) |
CYP76A26. |
Iridoid oxidase. |
Reaction catalysed |
(+)-cis,trans-nepetalactol + 3 [reduced NADPH--hemoprotein reductase] + 3 O(2) <=> 7-deoxyloganetate + 3 [oxidized NADPH--hemoprotein reductase] + 4 H(2)O |
Comment(s) |
- The enzyme, characterized from the plant Catharanthus roseus, is a
cytochrome P450 (heme thiolate) protein.
- It catalyzes three successive reactions in the pathway leading to
biosynthesis of monoterpenoid indole alkaloids.
|
Cross-references |
BRENDA | 1.14.14.161 |
EC2PDB | 1.14.14.161 |
ExplorEnz | 1.14.14.161 |
PRIAM enzyme-specific profiles | 1.14.14.161 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.161 |
IUBMB Enzyme Nomenclature | 1.14.14.161 |
IntEnz | 1.14.14.161 |
MEDLINE | Find literature relating to 1.14.14.161 |
MetaCyc | 1.14.14.161 |
UniProtKB/Swiss-Prot |
|
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