ENZYME entry: EC 1.14.14.161
| Accepted Name |
|---|
| nepetalactol monooxygenase.
|
| Alternative Name(s) |
|---|
| CYP76A26. |
| iridoid oxidase. |
| Reaction catalysed |
|---|
| (+)-cis-trans-nepetalactol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 7-deoxyloganetate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] |
| Comment(s) |
|---|
- The enzyme, characterized from the plant Catharanthus roseus, is a
cytochrome P450 (heme thiolate) protein.
- It catalyzes three successive reactions in the pathway leading to
biosynthesis of monoterpenoid indole alkaloids.
|
| Cross-references |
|---|
| BRENDA | 1.14.14.161 |
| EC2PDB | 1.14.14.161 |
| ExplorEnz | 1.14.14.161 |
| PRIAM enzyme-specific profiles | 1.14.14.161 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.161 |
| IUBMB Enzyme Nomenclature | 1.14.14.161 |
| IntEnz | 1.14.14.161 |
| MEDLINE | Find literature relating to 1.14.14.161 |
| MetaCyc | 1.14.14.161 |
| Rhea expert-curated reactions | 1.14.14.161 |
| UniProtKB/Swiss-Prot |
|
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