Home  |  Contact

ENZYME entry: EC 1.14.14.161

Accepted Name
nepetalactol monooxygenase.
Alternative Name(s)
CYP76A26.
iridoid oxidase.
Reaction catalysed
(+)-cis-trans-nepetalactol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 7-deoxyloganetate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]
Comment(s)
  • The enzyme, characterized from the plant Catharanthus roseus, is a cytochrome P450 (heme thiolate) protein.
  • It catalyzes three successive reactions in the pathway leading to biosynthesis of monoterpenoid indole alkaloids.
Cross-references
BRENDA1.14.14.161
EC2PDB1.14.14.161
ExplorEnz1.14.14.161
PRIAM enzyme-specific profiles1.14.14.161
KEGG Ligand Database for Enzyme Nomenclature1.14.14.161
IUBMB Enzyme Nomenclature1.14.14.161
IntEnz1.14.14.161
MEDLINEFind literature relating to 1.14.14.161
MetaCyc1.14.14.161
Rhea expert-curated reactions1.14.14.161
UniProtKB/Swiss-Prot
W8JIS5, IO_CATRO

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-