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ENZYME entry: EC 1.14.14.163

Accepted Name
(S)-1-hydroxy-N-methylcanadine 13-hydroxylase.
Alternative Name(s)
CYP82X2.
Reaction catalysed
(S)-1-hydroxy-N-methylcanadine + [reduced NADPH--hemoprotein reductase] + O(2) <=> (13S,14R)-1,13-dihydroxy-N-methylcanadine + [oxidized NADPH--hemoprotein reductase] + H(2)O
Comment(s)
The enzyme, characterized from the plant Papaver somniferum (opium poppy), participates in the biosynthesis of the isoquinoline alkaloid noscapine.
Cross-references
BRENDA1.14.14.163
EC2PDB1.14.14.163
ExplorEnz1.14.14.163
PRIAM enzyme-specific profiles1.14.14.163
KEGG Ligand Database for Enzyme Nomenclature1.14.14.163
IUBMB Enzyme Nomenclature1.14.14.163
IntEnz1.14.14.163
MEDLINEFind literature relating to 1.14.14.163
MetaCyc1.14.14.163
UniProtKB/Swiss-Prot
I3PLR0, C82X2_PAPSO

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