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ENZYME entry: EC 1.14.14.166

Accepted Name
(S)-N-methylcanadine 1-hydroxylase.
Alternative Name(s)
CYP82Y1.
Reaction catalysed
(S)-N-methylcanadine + [reduced NADPH--hemoprotein reductase] + O(2) <=> (S)-1-hydroxy-N-methylcanadine + [oxidized NADPH--hemoprotein reductase] + H(2)O
Comment(s)
This cytochrome P450 (heme-thiolate) enzyme, characterized from the plant Papaver somniferum (opium poppy), participates in the biosynthesis of the isoquinoline alkaloid noscapine.
Cross-references
BRENDA1.14.14.166
EC2PDB1.14.14.166
ExplorEnz1.14.14.166
PRIAM enzyme-specific profiles1.14.14.166
KEGG Ligand Database for Enzyme Nomenclature1.14.14.166
IUBMB Enzyme Nomenclature1.14.14.166
IntEnz1.14.14.166
MEDLINEFind literature relating to 1.14.14.166
MetaCyc1.14.14.166
Rhea expert-curated reactions1.14.14.166
UniProtKB/Swiss-Prot
I3PLR1, C82Y1_PAPSO

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