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ENZYME entry: EC 1.14.14.167

Accepted Name
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase.
Alternative Name(s)
CYP82X1.
Reaction catalysed
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + [reduced NADPH--hemoprotein reductase] + O(2) <=> (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + [oxidized NADPH--hemoprotein reductase] + H(2)O
Comment(s)
This cytochrome P450 (heme-thiolate) enzyme, characterized from the plant Papaver somniferum (opium poppy), participates in the biosynthesis of the isoquinoline alkaloid noscapine.
Cross-references
BRENDA1.14.14.167
EC2PDB1.14.14.167
ExplorEnz1.14.14.167
PRIAM enzyme-specific profiles1.14.14.167
KEGG Ligand Database for Enzyme Nomenclature1.14.14.167
IUBMB Enzyme Nomenclature1.14.14.167
IntEnz1.14.14.167
MEDLINEFind literature relating to 1.14.14.167
MetaCyc1.14.14.167
Rhea expert-curated reactions1.14.14.167
UniProtKB/Swiss-Prot
I3V6B7, C82X1_PAPSO

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