ENZYME entry: EC 1.14.14.167
| Accepted Name | ||
|---|---|---|
| (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase | ||
| Alternative Name(s) | ||
| CYP82X1 | ||
| Reaction catalysed | ||
| (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] <=> (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] | ||
| Comment(s) | ||
| This cytochrome P450 (heme-thiolate) enzyme, characterized from the plant Papaver somniferum (opium poppy), participates in the biosynthesis of the isoquinoline alkaloid noscapine. | ||
| Cross-references | ||
| BRENDA | 1.14.14.167 | |
| EC2PDB | 1.14.14.167 | |
| ExplorEnz | 1.14.14.167 | |
| PRIAM enzyme-specific profiles | 1.14.14.167 | |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.167 | |
| IUBMB Enzyme Nomenclature | 1.14.14.167 | |
| IntEnz | 1.14.14.167 | |
| MEDLINE | Find literature relating to 1.14.14.167 | |
| MetaCyc | 1.14.14.167 | |
| Rhea expert-curated reactions | 1.14.14.167 | |
| UniProtKB/Swiss-Prot |
| |
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