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ENZYME

ENZYME entry: EC 1.14.14.167

Accepted Name
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine 8-hydroxylase
Alternative Name(s)
CYP82X1
Reaction catalysed
(13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] = (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]
Comment(s)
This cytochrome P450 (heme-thiolate) enzyme, characterized from the plant Papaver somniferum (opium poppy), participates in the biosynthesis of the isoquinoline alkaloid noscapine.
Cross-references
BRENDA1.14.14.167
EC2PDB1.14.14.167
ExplorEnz1.14.14.167
PRIAM enzyme-specific profiles1.14.14.167
KEGG Ligand Database for Enzyme Nomenclature1.14.14.167
IUBMB Enzyme Nomenclature1.14.14.167
IntEnz1.14.14.167
MEDLINEFind literature relating to 1.14.14.167
MetaCyc1.14.14.167
Rhea expert-curated reactions1.14.14.167
UniProtKB/Swiss-Prot
I3V6B7, C82X1_PAPSO

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