ID 1.14.14.177 DE ultra-long-chain fatty acid omega-hydroxylase. AN CYP4F22. CA an omega-methyl-ultra-long-chain fatty acid + O2 + reduced [NADPH- CA -hemoprotein reductase] = an omega-hydroxy-ultra-long-chain fatty acid + CA H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. CC -!- The enzyme, which is expressed in the epidermis of mammals, catalyzes CC the omega-hydroxylation of ultra-long-chain fatty acids (C28 to C36). CC -!- The products are incorporated into acylceramides, epidermis-specific CC ceramide species that are very important for skin barrier formation. DR Q6NT55, CP4FN_HUMAN; //