ID 1.14.14.177 DE Ultra-long-chain fatty acid omega-hydroxylase. AN CYP4F22. CA An ultra-long-chain fatty acid + [reduced NADPH--hemoprotein reductase] + CA O(2) = an ultra-long-chain omega-hydroxy fatty acid + [oxidized NADPH- CA -hemoprotein reductase] + H(2)O. CC -!- The enzyme, which is expressed in the epidermis of mammals, catalyzes CC the omega-hydroxylation of ultra-long-chain fatty acids (C(28) to CC C(36)). CC -!- The products are incorporated into acylceramides, epidermis-specific CC ceramide species that are very important for skin barrier formation. DR Q6NT55, CP4FN_HUMAN; //