ID   1.14.14.178
DE   steroid 22S-hydroxylase.
AN   CYP90B1.
AN   steroid C-22 hydroxylase.
CA   (1) a C27-steroid + reduced [NADPH--hemoprotein reductase] + O2 =
CA   a (22S)-22-hydroxy C27-steroid + oxidized [NADPH--hemoprotein reductase]
CA   + H2O + H(+).
CA   (2) a C28-steroid + reduced [NADPH--hemoprotein reductase] + O2 =
CA   a (22S)-22-hydroxy C28-steroid + oxidized [NADPH--hemoprotein reductase]
CA   + H2O + H(+).
CA   (3) a C29-steroid + reduced [NADPH--hemoprotein reductase] + O2 =
CA   a (22S)-22-hydroxy C29-steroid + oxidized [NADPH--hemoprotein reductase]
CA   + H2O + H(+).
CC   -!- This plant cytochrome P450 (heme thiolate) enzyme participates in the
CC       biosynthesis of brassinosteroids.
CC   -!- While in vivo substrates include C28-steroids such as campestanol,
CC       campesterol, and 6-oxocampestanol, the enzyme is able to catalyze the
CC       C-22 hydroxylation of a variety of C27, C28 and C29 steroids.
DR   O64989, C90B1_ARATH;  I1H7R8, C90B1_BRADI;  B8AJL3, C90B2_ORYSI;
DR   Q5CCK3, C90B2_ORYSJ;
//