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ENZYME

ENZYME entry: EC 1.14.14.183

PURL: https://purl.expasy.org/enzyme/EC/1.14.14.183
Accepted Name
taxoid 2alpha-hydroxylase
Reaction catalysed
  • taxusin + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha-hydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
  • 7beta-hydroxytaxusin + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha,7beta-dihydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Comment(s)
  • A cytochrome P450 (heme-thiolate) protein from the yew tree Taxus cuspidata.
  • Does not act on earlier intermediates in taxol biosynthesis.
Cross-references
BRENDA1.14.14.183
EC2PDB1.14.14.183
ExplorEnz1.14.14.183
KEGG Ligand Database for Enzyme Nomenclature1.14.14.183
IUBMB Enzyme Nomenclature1.14.14.183
MEDLINEFind literature relating to 1.14.14.183
MetaCyc1.14.14.183
Rhea expert-curated reactions1.14.14.183

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-