ID   1.14.14.184
DE   5-dehydro-6-demethoxyfumagillol synthase.
AN   Fma-P450.
AN   fumagillin multifunctional cytochrome P450 monooxygenase.
CA   (+)-exo-beta-bergamotene + 3 O2 + 2 reduced [NADPH--hemoprotein
CA   reductase] = 5-dehydro-6-demethoxyfumagillol + 2 H(+) + 3 H2O +
CA   2 oxidized [NADPH--hemoprotein reductase].
CC   -!- The enzyme, characterized from the mold Aspergillus fumigatus,
CC       catalyzes a complex transformation comprising hydroxylation, bicyclic
CC       ring-opening, and two epoxidations, generating the sesquiterpenoid
CC       core skeleton of fumagillin.
DR   Q4WAZ6, FMAG_ASPFU ;
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