ENZYME entry: EC 1.14.14.185
| Accepted Name | |
|---|---|
| taxane 9alpha-hydroxylase | |
| Alternative Name(s) | |
| CYP725A22 | |
| taxoid 9alpha hydroxylase | |
| Reaction catalysed | |
| O2 + oxo-taxadiene-4alpha-ol + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + oxo-taxadiene-4alpha,9alpha-diol | |
| Comment(s) | |
| The enzyme is active in the biosynthetic pathway of paclitaxel (Taxol) in Taxus species (yew). | |
| Cross-references | |
| BRENDA | 1.14.14.185 |
| EC2PDB | 1.14.14.185 |
| ExplorEnz | 1.14.14.185 |
| PRIAM enzyme-specific profiles | 1.14.14.185 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.185 |
| IUBMB Enzyme Nomenclature | 1.14.14.185 |
| IntEnz | 1.14.14.185 |
| MEDLINE | Find literature relating to 1.14.14.185 |
| MetaCyc | 1.14.14.185 |
| Rhea expert-curated reactions | 1.14.14.185 |
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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-