ENZYME entry: EC 1.14.14.192
| Accepted Name | ||
|---|---|---|
| taxoid 1beta-hydroxylase | ||
| Alternative Name(s) | ||
| CYP725 A23-1 | ||
| taxane 1beta-hydroxylase | ||
| Reaction catalysed | ||
| 10-deacetyl-1-deoxybaccatin III + reduced [NADPH--hemoprotein reductase] + O2 = 10-deacetylbaccatin III + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) | ||
| Comment(s) | ||
| A cytochrome P450 (heme thiolate) enzyme involved in paclitaxel (taxol) biosynthesis. Isolated from the plant Taxus baccata (English yew). | ||
| Cross-references | ||
| Rhea expert-curated reactions | 1.14.14.192 | |
| ExplorEnz | 1.14.14.192 | |
| IUBMB Enzyme Nomenclature | 1.14.14.192 | |
| UniProtKB/Swiss-Prot |
| |
| BRENDA | 1.14.14.192 | |
| MetaCyc | 1.14.14.192 | |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.14.192 | |
| MEDLINE | Find literature relating to 1.14.14.192 | |
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