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ENZYME

ENZYME entry: EC 1.14.14.193

PURL: https://purl.expasy.org/enzyme/EC/1.14.14.193
Accepted Name
taxol side chain-2'-hydroxylase
Alternative Name(s)
CYP73A171
Reaction catalysed
3'-N-debenzoyl-2'-deoxytaxol + reduced [NADPH--hemoprotein reductase] + O2 = 3'-N-debenzoyltaxol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Comment(s)
  • A cytochrome P450 (heme thiolate) enzyme isolated from the plant Taxus x media.
  • The penultimate step in paclitaxel (taxol) biosynthesis.
Cross-references
BRENDA1.14.14.193
EC2PDB1.14.14.193
ExplorEnz1.14.14.193
KEGG Ligand Database for Enzyme Nomenclature1.14.14.193
IUBMB Enzyme Nomenclature1.14.14.193
MEDLINEFind literature relating to 1.14.14.193
MetaCyc1.14.14.193
Rhea expert-curated reactions1.14.14.193

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.14.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-