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ENZYME

ENZYME entry: EC 1.14.14.194

PURL: https://purl.expasy.org/enzyme/EC/1.14.14.194
Accepted Name
ecgonone synthase
Alternative Name(s)
CYP81AN15
CYP82M3
Reaction catalysed
(S)-4-(1-methylpyrrolidin-2-yl)-3-oxobutanoate + reduced [NADPH--hemoprotein reductase] + O2 = (+)-ecgonone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Comment(s)
  • A cytochrome P450 (heme thiolate) enzyme that has been isolated from the plants Atropa belladonna, Erythroxylum novogranatense and Anisodus acutangulus.
  • It participates in biosynthesis of assorted tropane alkaloids.
Cross-references
Rhea expert-curated reactions1.14.14.194
ExplorEnz1.14.14.194
IUBMB Enzyme Nomenclature1.14.14.194
UniProtKB/Swiss-Prot
A0A9E9NIU8, C81AN_ERYCBA0A9E8M4C5, C81AN_ERYNOA0A3G4RHY7, C82M3_ATRBE
A0A9Y1E1K8, C82M3_DATST
BRENDA1.14.14.194
MetaCyc1.14.14.194
KEGG Ligand Database for Enzyme Nomenclature1.14.14.194
MEDLINEFind literature relating to 1.14.14.194

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